Brain Arousal and Information Theory
Neural and Genetic Mechanisms
Donald Pfaff
Preface and Dedication
1. Toward a Universal Theory of Brain Arousal
What Is to Be Explained? Ethology and the Mechanisms of Arousal
Operational Definition of Arousal
A Quantitative Approach to Physical Measurement of Generalized Arousal
The Neurobiology of Arousal Constitutes an Interesting Application of Information Theory
Claims for This Chapter and Introduction to Chapters Following
2. Anatomy Is Not Destiny, but a Little Neuroanatomy Helps
Multiplicity and Redundancy of Ascending Arousal Pathways Prevent Failure
Primitive "Master Cells" in the Brainstem Provide a Neuroanatomic Core that Theoretically Matches the Behavioral Data
Long-Distance Lines Tuning Local Modules
Summary and Hypothetical Implications for Human Behavior
3. Arousal Is Signaled by Electrical Discharges in a System of Nerve Cells
Traveling Up the Brainstem
Special Cases: Olfaction and Vision
Informational Content Governs Amplitude of Response in Neurons Related to Arousal
Cerebral Cortex, the EEG
Electrical Activity in Three Arousal-Related Biological Systems
4. Autonomic Nervous System Changes Supporting Arousal; the Unity of the Body
Patterns of Autonomic Responses
Reformulations
A High Information System Shows Coordination sans Correlation
Supporting Hormone-Dependent Behaviors
Summary
5. Genes Whose Neurochemical Products Support Arousal
Genes Associated with Classical Systems
Genes Newly Recognized
Concepts and Questions
Summary
6. Heightened States of Arousal: Sex Compared to Fear
Sex Behavior's CNS Mechanisms Require Arousal
Generalized Arousal Affects Specific Arousals and Vice Versa
Contrast Sex and Fear
Applicability of Information Theory
Libido and Stress in Humans
Summary
7. Major Systems Questions about Brain Arousal Networks
What Are Universal Operating Features of Arousal Systems?
How Do We Meet the Requirement for Rapid Changes of CNS State?
Sensitivity and Alacrity of Response, Yet Stability? How?
Does Automata Theory Apply?
Questions in the Time Domain
Questions about Spatial Properties
Thermodynamics, Information Theory, and Questions for the CNS
How Does a Sine Wave Impact a Sawtooth?
Unity from Diversity?
8. Summary and Practical Importance: From Biological Mechanisms to Health Applications
Main Points
Applications to Human Conditions
Works Cited
Acknowledgments
Index


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