Cover: The Biology of Cell Reproduction, from Harvard University PressCover: The Biology of Cell Reproduction in HARDCOVER

The Biology of Cell Reproduction

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Product Details


$84.00 • £67.95 • €75.50

ISBN 9780674074064

Publication Date: 05/01/1985


251 pages

33 figures, 25 tables


  • I. Biology
    • 1. The Cell Cycle
      • Phases of the cell cycle
      • Variability of the cell cycle
    • 2. Nondividing Cells
      • G0 cells
      • Terminally differentiated cells
    • 3. Populations of Cells
      • Stem cells
      • Transformed cells
    • 4. Tissue Growth
      • Growth in size
      • Growth in number
      • Doubling time
      • Growth of tumors
    • 5. Synchronization of Cells in the Cell Cycle
      • Methods for synchronizing cells in culture
      • Morphology of cells during the cell cycle
  • II. Cell Biology
    • 6. Temperature-Sensitive Mutants of the Cell Cycle
      • Defining cell cycle mutants
      • Conditional cell cycle mutants
      • The execution point
    • 7. Informational Content of Cells in Different Phases of the Cell Cycle
      • Cell fusion
      • Informational content of S phase cells
      • Informational content of G0-G cells
      • Premature chromosome condensation
    • 8. Perturbation of the Cell Cycle by Drugs
      • Actinomycin D
      • Cycloheximide
      • Other drugs
      • Monoclonal antibodies
    • 9. Growth in Size and Cell Proliferation
      • Growth in size and cell DNA replication
      • Growth in size and cell division
      • The role of RNA polymerase II
  • III. Molecular Biology
    • 10. The Environmental Signals
      • Growth factors
      • Inhibitory factors
    • 11. Biochemical Events in the Cell Cycle
      • Does the cell cycle exist?
      • Controlling events and prerequisite events
      • G1 and G0
      • S phase
      • G2 and mitosis
    • 12. Virally-Coded Proteins and Cell Proliferation
      • SV4O and polyoma
      • Adenovirus
      • Other viruses
      • Mechanisms of viral-induced cell DNA replication
    • 13. Genetic Basis of Cell Proliferation
      • Cdc genes in yeasts
      • Retroviral oncogenes
      • Cellular oncogenes
      • Cdc genes in animal cells
      • Some speculations
  • References
  • Index

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