Cover: Body and Brain in PAPERBACK

Body and Brain

A Trophic Theory of Neural Connections

Add to Cart

Product Details

PAPERBACK

$37.50 • £30.95 • €34.00

ISBN 9780674077164

Publication Date: 10/01/1990

Short

240 pages

6-3/8 x 9-1/4 inches

12 halftones, 73 line illustrations, 3 tables

World

The major goal of developmental neurobiology is to understand how the nervous system is put together. A central theme that has emerged from research in this field over the last several decades is the crucial role of trophic interactions in neural assembly, and indeed throughout an animal’s life. Trophic—which means nutritive—refers to long-term interdependencies between nerve cells and the cells they innervate.

The theory of trophic effects presented in this book offers an explanation of how the vertebrate nervous system is related to—and regulated by—the body it serves. The theory rationalizes the nervous system’s accommodation, throughout life, to the changing size and form of the body it tenants, indicating the way connections between nerve cells change in response to stimuli as diverse as growth, injury, experience, and natural selection.

Dale Purves, a leading neurobiologist best known for his work on the formation and maintenance of synaptic connections, presents this theory within the historical setting of earlier ideas about neural organization—from Weiss’s theory of functional reorganization to the chemoaffinity theory championed by Sperry. In addition to illuminating eighty years of work on trophic interactions, this book asks its own compelling questions: Are trophic interactions characteristic of all animals or only of those with complex nervous systems? Are trophic interactions related to learning? What does the trophic theory of neural connections imply about the currently fashionable view that the nervous system operates according to Darwinian principles?

Purves lays the theoretical foundation for practical exploration of trophic interactions as they apply to neural connections, a pursuit that will help us understand how our own nervous systems generate change. The ideas in this book not only enrich neurobiology but also convey the profound relevance of neuroscience to other fields of life science.

Recent News

From Our Blog

Photo of Lucia Jacobs as a child sitting next to Oaky

How to Plant a Forest

For this week’s University Press Week Blog Tour, Lucia Jacobs offers us a glimpse of environmental stewardship as seen through the activities of the ubiquitous squirrel, a species native to the Americas, Africa, and Eurasia from the Eocene Epoch onward. Lucia Jacobs is Professor of Psychology and Neuroscience at the

‘manifold glories of classical Greek and Latin’

The digital Loeb Classical Library (loebclassics.com) extends the founding mission of James Loeb with an interconnected, fully searchable, perpetually growing virtual library of all that is important in Greek and Latin literature.