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P. W. Bridgman received the 1946 Nobel Prize in physics in recognition of his pioneering research on the effects of high pressures on the behavior of matter. That work, which extended over a period of half a century and was carried out with equipment and measuring techniques which he himself had to design and develop, led to vast increases in the pressures obtainable under laboratory conditions and to measurements of the compressibility of a large number of materials, of the viscosity of liquids under pressure, of changes in phase, and of numerous other properties of materials which had been subjected to high pressures. He once observed that from the cosmic point of view it is important to understand the effects of pressures “because all except a small fraction of one percent of the matter in the universe exists under pressures greater than 1000 atmospheres.” Pressures produced in his laboratory eventually exceeded that figure by more than 400 times. These papers constitute the record of the experimental work in the physics of high pressure to which Bridgman devoted most of his scientific efforts. Extending over a period of fifty years, all of the experimental papers are here reproduced as they originally appeared. A small number have been reset to fit the present format but the rest have been reproduced photographically. A complete index of substances, based on one prepared by the author, and an index of subjects including apparatus and techniques are provided.