Cover: The Pathway for Oxygen: Structure and Function in the Mammalian Respiratory System, from Harvard University PressCover: The Pathway for Oxygen in PAPERBACK

The Pathway for Oxygen

Structure and Function in the Mammalian Respiratory System

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$52.00 • £45.95 • €47.95

ISBN 9780674657908

Publication Date: 01/01/1984


448 pages

124 line illustrations, 61 halftones, 18 tables


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Related Subjects

  • 1. Oxygen and the History of Life
    • The Cell’s Oxygen Sink and Energetics
    • Getting Oxygen to the Sink
    • Evolution of O2 Transport Systems
    • Evolution of External Gas Exchangers
    • Looking at the System as a Whole: Philosophy of the Approach
  • 2. The Body’s Need For Oxygen
    • Levels of O2 Consumption
    • Estimating the Limits of O2 Consumption
  • 3. Linking Structure and Function: Model, Means, and Tools
    • How Does Structure Affect O2 Flow?
    • Are Animals Built Reasonably?
    • The Tools
  • 4. Cell Respiration
    • Gaining Energy from Combustion
    • Metabolic Pathways of the Cell
    • The Cell’s Energetic Balance Sheet
  • 5. Mitochondria: The Cell’s Furnaces
    • Putting Some Order into Cell Metabolism
    • Oxidation–Phosphorylation Coupling Depends on Structure
    • Mitochondria and the Cell’s Aerobic Potential
    • Mitochondria in Muscle Cells
  • 6. The Vehicle For Oxygen Transport: Blood and Circulation
    • The O2 and CO2 Carrier: Blood
    • Moving Blood Around: Circulation
    • O2 Transport by the Blood
  • 7. Delivering Oxygen to the Cells
    • Distributing Blood to the Tissues: Design of the Vasculature
    • The Microvascular Unit
    • O2 Flow from Blood to Cells
  • 8. Design and Development of the Mammalian Lung
    • Development of the Lung
    • Lung Histogenesis: Differentiation toward Gas Exchange
    • The Lung at Birth and Its Postnatal Maturation
  • 9. Lung Cell Biology
    • Organization of the Lung’s Cell Population
    • A Closer Look at the Cells of the Gas Exchange Region
  • 10. Airways and Blood Vessels
    • The Airway Tree
    • Ventilation
    • The Vascular Trees
    • Pulmonary Blood Flow
    • Ventilation–Perfusion Matching
  • 11. The Lung’s Mechanical Support
    • External Support and Motive Force
    • The Pleural Cavity
    • The Lung’s Fiber Skeleton
    • Surface Tension
    • Micromechanics and the Configuration of the Alveolar Septum
    • Keeping the Barrier Dry and Thin
  • 12. The Lung as Gas Exchanger
    • Design of the Gas Exchanger
    • Physiological Basis for Gas Exchange
    • Pulmonary Diffusing Capacity: Physiology
    • Pulmonary Diffusing Capacity: Morphometry
    • Structure and Function Compared
    • Matching the Conductance to O2 Needs: The Emergence of a Paradox
    • Resolving the Paradox: Models and Nature
  • 13. The Respiratory System in Overview
    • Adjusting Performance to Needs
    • Adjusting Potential to Needs
    • The Limits to Potential: The Smallest Mammal
  • Units of Measurement
  • General References
  • Index

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