Cover: Venous Thrombosis and Pulmonary Embolism in HARDCOVER

Venous Thrombosis and Pulmonary Embolism

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HARDCOVER

$64.50 • £51.95 • €58.00

ISBN 9780674933200

Publication Date: 01/01/1970

Short

Related Subjects

  • 1. Incidence and Importance of Thromboembolism
    • Magnitude of the problem
    • Frequency of deep vein thrombosis
    • Pulmonary embolism
    • Is pulmonary embolism increasing?
    • Geographic and allied factors
    • Inevitable and potentially preventable deaths
  • 2. Pathology of Venous Thrombosis
    • Thrombus growth and evolution
    • Appearance and structure of thrombi
    • Histological structure
    • Platelet aggregates
    • Valve-cusp thrombi and nidus structure
    • Location and frequency of thrombi
    • Frequency of thrombi in leg, thigh, and pelvic veins
    • Sites of primary thrombosis
    • Ageing and resolution of thrombi
    • Leucocytes
    • Thrombolysis
    • Red cells and hemosiderin
    • Platelet phagocytosis and foam cells
    • Organization and canalization
    • Mural thrombi
    • Occlusive thrombi
    • Source of cells
  • 3. Predisposing Factors
    • Sex
    • ABO blood group
    • Age
    • Immobility and bedrest
    • Age and bedrest combined
    • Previous thromboembolism
    • Obesity
    • Medical and surgical
    • Heart disease
    • Cancer
    • Operation
    • Trauma
    • Pulmonary embolism after injury
    • Paralysis
    • Tetanus
    • Pregnancy and the puerperium
    • Oral contraceptives
    • Tuberculosis
    • Ulcerative colitis
    • Other possible associations
    • Seasonal variation
    • Anemia
    • Polycythemia
    • Thyroid disease
    • Idiopathic thrombosis and embolism
  • 4. Mechanisms of Venous Thrombosis
    • Vein wall
    • Venous anatomy
    • Soleal veins
    • Gastrocnemius veins
    • Posterior tibial and peroneal veins
    • Anterior tibial veins
    • Popliteal and superficial femoral veins
    • Common and profunda femoral veins
    • Iliac veins
    • Turbulence
    • Venous stasis
    • Extreme local stasis
    • Changes in the blood
  • 5. Experimental Venous Thrombosis
    • Coagulation
    • Hemostasis
    • Platelet aggregation
    • Experimental thrombosis
    • Thrombi in vitro
    • Thrombi in extracorporeal shunts
    • Studies in vivo
    • Serum-induced stasis thrombi
    • ADP and stasis thrombi
    • Reactions of the vessel wall to thrombi
  • 6. A Unified Concept of Pathogenesis
    • Nidus formation
    • Stabilization and propagation
    • Role of fibrinolysis
    • Retrograde extension
    • Clotting factors in venous thrombogenesis
    • Activation at a distance
    • Venous thrombosis without stasis
    • Clearance of activated clotting factors
  • 7. Silent Thrombosis and Unheralded Embolism
    • Silent thrombosis
    • Factors influencing silent and clinical thrombosis
    • Effect of gravity
    • Unheralded embolism
    • Frequency of embolism from silent thrombosis
  • 8. Clinical Features of Venous Thrombosis
    • Symptoms
    • Past history
    • Constitutional signs
    • Swelling
    • Local tenderness
    • Dorsiflexion of the foot
    • Warm leg
    • Cuff pain test
    • Venous claudication
    • Special forms of thrombosis
    • Phlegmasia alba dolens
    • Phlegmasia cerulea dolens
    • Special points in pathogenesis
    • Superficial thrombophlebitis
    • Thrombophlebitis migrans
    • “False phlebitis”
    • Arm swelling due to venous obstruction
    • Mondor’s disease
    • Suppurative thrombophlebitis
    • Thrombosis of the inferior vena cava
  • 9. Phlebography and Other Aids to the Diagnosis of Venous Thrombosis
    • Phlebography
    • Technique
    • Indications
    • Interpretation
    • Complications
    • Preferential localization of isotopes in propagating venous thrombosis
    • Doppler-effect flowmeter
    • Impedance plethysmography
    • Venous pressure
    • Thermography
    • Blood tests
  • 10. Statistical Applications to the Study of Venous Thrombosis
    • Selection of a subset of variables
    • Discriminant function
    • Appendix
  • 11. Pathology of Pulmonary Embolism
    • Morbid anatomy
    • Major emboli
    • Minor emboli
    • Secondary thrombosis
    • Multiplicity and distribution of emboli
    • Recurrent embolism
    • Paradoxical embolism
    • Source of the emboli
    • Source in clinical thrombosis
    • Thrombus detachment
    • Complications
    • Infarction
    • Pulmonary edema
    • Fate of emboli
    • Thrombolysis
    • Organization
    • Atheromatous plaques
    • Fibrous bands and webs
    • Sequelae
    • Bronchopulmonary and other lung anastomoses
    • Chronic pulmonary hypertension
  • 12. Pulmonary Microembolism
    • Arterial microthrombi
    • Significance and importance
    • Capillary microthrombi
    • Hemorrhage and trauma
    • Burns
    • Anaphylaxis
    • Bacterial endotoxin
    • Pathogenesis of capillary microthrombosis
    • Significance and importance of capillary microthrombi
    • Irreversible shock
    • By-pass surgery and microembolism from transfused blood
  • 13. Physiological Studies on Pulmonary Embolism
    • Cardiovascular reactions
    • Effect of heparin and the role of platelets
    • Pulmonary function
    • Pulmonary ventilation and perfusion after embolism
    • Clinical application
    • Humoral mechanisms
    • Physiological effects of pulmonary microembolism
    • Foreign-body microembolism
    • Platelet microembolism
    • Thrombolysis
    • Conclusions
  • 14. Clinical Features of Pulmonary Embolism
    • Massive embolism
    • Lobar, multiple, and micro-embolism
    • Symptoms and signs
    • Dyspnea and tachypnea
    • Chest pain
    • Cough, hemoptysis, and chest signs
    • Cyanosis, tachycardia, fever
    • Cardiovascular signs
    • Clinical syndromes of embolism and differential diagnosis
    • Pneumonic syndrome
    • Acute hypotension
    • Acute congestive failure and cor pulmonale
    • Sudden collapse
    • Gradual deterioration
    • Pulmonary infarction
    • Abcess formation
    • Embolic detachment
    • Day of onset of embolism
    • Embolism in clinical thrombosis
    • Aids to diagnosis
    • Electrocardiography
    • Pulmonary function studies
    • Enzyme studies
    • The approach to diagnosis
    • Major symptoms
    • Massive embolism
  • 15. Radiology and Lung Scanning in Diagnosis of Pulmonary Embolism
    • Radiology in pulmonary embolism
    • Massive pulmonary embolism
    • Plain films
    • Angiography
    • Emboli in branch arteries
    • Plain films
    • Angiography
    • Small peripheral embolism and chronic pulmonary hypertension
    • Plain films
    • Angiography
    • Pulmonary thrombosis
    • Veno-occlusive disease
    • Radioisotope lung scanning
    • Pulmonary embolism
    • Branch embolism
    • Differential diagnosis with angiography and lung scanning
  • 16. Prevention of Venous Thrombosis and Pulmonary Embolism
    • Physical activity
    • Clinical experience
    • Prophylactic calf muscle contraction during surgery
    • Elastic compression of the limbs
    • Anticoagulant prophylaxis
    • Early trials
    • Controlled trials
    • Indications
    • Trauma
    • Burns
    • Orthopedic surgery
    • Gynecologic surgery
    • Thoracic cardiac surgery
    • Abdominal and other surgery
    • Preoperative institution of prophylaxis
    • Pregnancy and the puerperium
    • Medical cases
    • Short-term heparin prophylaxis
    • Prophylaxis with dextran
    • Clinical experience
    • Dextran and oral anticoagulants
    • Other agents
    • Streptokinase
    • Anti-platelet agents
  • 17. Medical Treatment
    • Anticoagulant therapy
    • Heparin
    • Administration
    • Dosage
    • Duration of therapy for pulmonary embolism
    • Treatment of venous thrombosis
    • Oral anticoagulant therapy
    • Thrombolytic therapy
    • Experimental thrombolysis
    • Human studies
    • Dextran therapy
    • Therapeutic defibrination
    • Platelet active agents
    • Ancillary and supportive treatment
    • Pulmonary embolism
    • Venous thrombosis
  • 18. Oral Anticoagulant Therapy
    • History
    • Properties of coumarin and indanedione drugs
    • Pharmacology
    • Hypoprothrombinemia
    • Effects on platelets
    • Other properties
    • Drugs in common use
    • Nicoumalone
    • Sodium warfarin
    • Phenindione
    • Dicumoral
    • Phenprocoumon
    • Laboratory tests for control of dosage
    • Prothrombin time (one stage test)
    • Thromboplastin
    • Thrombotest
    • Therapeutic aims and range
    • Partial thromboplastin time
    • The balance between antithrombotic action and hemorrhagic complications
    • Factors influencing therapeutic dosage and response
    • Effect of certain drugs
    • Drug resistance
    • Hemorrhagic complications
    • Types of hemorrhage
    • Frequency of hemorrhage
    • Avoidable hemorrhage
    • Management of hemorrhage
    • Contra-indications to anticoagulant therapy
    • General management
    • Emotional reactions
    • Centralized control of therapy
  • 19. Surgical Management
    • Phlegmasia alba dolens
    • Phlegmasia cerulea dolens
    • Arm vein thrombosis
    • Superficial thrombophlebitis
    • Surgery for pulmonary embolism
    • Suppurative thrombophlebitis with pulmonary embolism
    • Vein interruption as prophylaxis
    • Surgery preferred over anticoagulants for the control of overt thrombosis and embolism
    • Anticoagulants positively contraindicated
    • Failure of anticoagulants
    • Choice of ligation site
    • Caval septation, plication, and clipping
    • Embolization after ligation
    • Pulmonary embolectomy
  • 20. Chronic Venous Insufficiency
    • Management of chronic venous insufficiency
    • Local care of venous ulcers
    • Relief of venous hypertension
    • Bedrest
    • Local compression
    • Interruption of perforating veins
    • Injection therapy
    • Cross-over grafts of veins
    • Lymphedema secondary to venous thrombosis
    • Surgery

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